Media Extraction and analysis of high-quality chloroplast DNA with reduced nuclear DNA for medicinal plants
 
 

Extraction and analysis of high-quality chloroplast DNA with reduced nuclear DNA for medicinal plants

2025-01-15 20:45:07| Spiritual Career Counseling

Research Open access Published: 18 April 2024 Yifan Yu1,2, Xinxin Wang1, Renjun Qu1, Zhen OuYang2, Juan Guo1, Yujun Zhao1 & Luqi Huang1,2 BMC Biotechnology volume24, Articlenumber:20 (2024) Cite this article 1502 Accesses 1 Citations Metrics details AbstractBackgroundObtaining high-quality chloroplast genome sequences requires chloroplast DNA (cpDNA) samples that meet the sequencing requirements. The quality of extracted cpDNA directly impacts the efficiency and accuracy of sequencing analysis. Currently, there are no reported methods for extracting cpDNA from Erigeron breviscapus. Therefore, we developed a suitable method for extracting cpDNA from E. breviscapus and further verified its applicability to other medicinal plants.ResultsWe conducted a comparative analysis of chloroplast isolation and cpDNA extraction using modified high-salt low-pH method, the high-salt method, and the NaOH low-salt method, respectively. Subsequently, the number of cpDNA copies relative to the nuclear DN...


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